Submission of the use of the method of preemtive analgesia with acetaminophen for perioperative period in children
In the structure of postoperative anesthesia in children, as well as in other age groups, the main place is occupied by narcotic analgesics; the route of administration is traditional– intramuscular. The purpose of the study was to in-crease the effectiveness of postoperative analgesia with opioid analgesics in children. The study was conducted in 37 children with a mean age of 3.2 ± 0.8 years operated on tumors in the peritoneal space (27 children, 73%), kidney tumors (8chil-dren, 22%) and ovarian tumors (2 children, 5%). Comprehensive study of the reactions of pain behavior, physiological parameters and laboratory stress tests showed that the use of the scheme of analgesia based on acetaminophen 30 mg/kg and the method of continuous infusion of drugs (fentanyl in a dose of 5 μg/kg/h) for postoperative anesthesia leads to effective analgesia after traumatic operations in the neonatal period. The use of the method of continuous intravenous infusion of opioid analgesics leads to a pronounced, to varying degrees, sedation and respiratory depression, which enables children to adapt well to the apparatus of mechanical ventilation after various surgical interventions.
Veteshev PS, Vetesheva MS. Principy analgezii v rannem posleoperacionnom periode (Principles of analgesia in the early postoperative period). Hirurgiya. 2002;12:49–52. (In Russian)
Lekmanov AU. Vnutrivennoe ispolzovanie tramadola dlya posleoperacionnoj analgezii u detej (Intravenous use of tramadol for postoperative analgesia in children). Materialy VIII Vserossijskogo sezda anesteziologov reanimatologov. 1999:14–7. (In Russian)
Osipova NA, Nikoda VV. Sovremennoe sostoyanie nauki o boli (The current state of the science of pain). Anesteziologiya i reanimatologiya. 2003;5(4):4–9. (In Russian)
Morgan GE, Mikhail MS, Murray MJ. Clinical anesthesiology. New York: Lange Medical Books/McGraw-Hill; 2006.
Karavaeva SA, Bairov VG, Nemilova TK. Lechenie gastroshizisa (Gastroschisis treatment). Detskaya hirurgiya. 1998;3:4–7. (In Russian)
Woolf CJ, Chong M-S. Preemptive Analgesia—Treating Postoperative Pain by Preventing the Establishment of Central Sensitization. Anesthesia & Analgesia [Internet]. Ovid Technologies (Wolters Kluwer Health); 1993 Aug;77(2):362–79. Available from: https://doi.org/10.1213/00000539-199377020-00026
Eide PK, Stubhaug A, Øye I. 8 The NMDA-antagonist ketamine for prevention and treatment of acute and chronic post-operative pain. Baillière’s Clinical Anaesthesiology [Internet]. Elsevier BV; 1995 Sep;9(3):539–54. Available from: https://doi.org/10.1016/s0950-3501(95)80021-2
Brennum J, Petersen KL, Horn A, Arendt-Nielsen L, Secher NH, Jensen TS. Quantitative sensory examination of epidural anaesthesia and analgesia in man: combination of morphine and bupivacaine. Pain [Internet]. Ovid Technologies (Wolters Kluwer Health); 1994 Mar;56(3):327–37. Available from: https://doi.org/10.1016/0304-3959(94)90171-6
Nesteroidnye protivovospalitelnye sredstva v terapii onkologicheskoj boli (Nonsteroidal anti-inflammatory drugs in the treatment of cancer pain). Hirurgiya. 2006;8(2):15–25. (In Russian)
Vittinghoff M, Lönnqvist P-A, Mossetti V, Heschl S, Simic D, Colovic V, et al. Postoperative pain management in children: Guidance from the pain committee of the European Society for Paediatric Anaesthesiology (ESPA Pain Management Ladder Initiative). Pediatric Anesthesia [Internet]. Wiley; 2018 Apr 10;28(6):493–506. Available from: https://doi.org/10.1111/pan.13373
Hopf HW. Postoperative Pain Management. Archives of Surgery [Internet]. American Medical Association (AMA); 1994 Feb 1;129(2):128. Available from: https://doi.org/10.1001/archsurg.1994.01420260014002
Kalso E, Perttunen K, Kaasinen S. Pain after thoracic surgery. Acta Anaesthesiologica Scandinavica [Internet]. Wiley; 1992 Jan;36(1):96–100. Available from: https://doi.org/10.1111/j.1399-6576.1992.tb03430.x
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