Nefopam hydrochloride as a component of multimodal analgesia in the postoperative period

Authors

  • Andrii Semenenko National Pirogov Memorial Medical University, Vinnytsia

DOI:

https://doi.org/10.31636/pmjua.v5i2.4

Keywords:

nefopam hydrochloride, pain, tremor

Abstract

The modern approach to the multimodal scheme of postoperative analgesia includes the mandatory use of drugs that have a small number of side effects and at the same time have a polymodal effect on the pathogenetic links of pain development. Nefopam hydrochloride is able to prevent the development of: opioid hyperalgesia, stop pain stimuli without respiratory depression, affect platelet aggregation and the condition of the mucous membrane and motility of the gastrointestinal tract, which distinguishes it from classical NSAIDs. Nefopam hydrochloride is characterized by a low risk of addiction with prolonged use, a pronounced anti-sensory effect, especially significant at the stage of awakening and in the early postoperative period.

Postoperative analgesia based on nefopam hydrochloride as a component of multimodal analgesia is effective and safe in the absence of absolute contraindications. The planned use of nefopam hydrochloride for the correction of pain reduces complications in the postoperative period and improves the quality of life of patients. Nefopam hydrochloride is one of the most effective drugs for the correction of postoperative tremor syndrome. The use of nefopam hydrochloride as a drug, which is a part of premedication before surgical interventions and a component of multimodal analgesia, improves the quality of the postoperative period due to: reduction of pain syndrome, planned correction of postoperative tremor syndrome and correction of complications arising from inadequate treatment of pain syndrome.

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Нефопам гідрохлорид як компонент мультимодальної аналгезії у післяопераційному періоді

Published

2020-06-30

How to Cite

1.
Semenenko A. Nefopam hydrochloride as a component of multimodal analgesia in the postoperative period. PMJUA [Internet]. 2020Jun.30 [cited 2020Sep.29];5(2):68-75. Available from: https://www.painmedicine.org.ua/index.php/pnmdcn/article/view/225